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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $688 | 35 days |
Description | Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning. |
Molecular Weight | 895.096 |
Formula | C50H70O14 |
Cas No. | 79580-28-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | Ethyl Acetate: Soluble |
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