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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Bromo-PEG1-NH2 hydrobromide is a polyethylene glycol (PEG)-based linker compound employed in the synthesis of proteolysis-targeting chimeras (PROTACs). |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | Bromo-PEG1-NH2 hydrobromide |
Molecular Weight | 248.946 |
Formula | C4H11Br2NO |
Cas No. | 2287287-20-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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