bromo peg1 nh2 hydrobromide

Bromo-PEG1-NH2 hydrobromide, a polyethylene glycol (PEG)-based linker compound, is used in the synthesis of proteolysis-targeting chimeras (PROTACs).

NH2-C2-NH-Boc (PROTAC Linker 22), an alkyl chain-based PROTAC linker, can be used in the synthesis of PROTACs.

NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].

NH2-C4-NH-Boc (compound 15) is a PROTAC linker of the Alkyl ether class, suitable for synthesizing various PROTAC molecules.

1-Bromo-6-chlorohexane (Hexane, 1-bromo-6-chloro-) is used as PROTAC linker.

Boc-NH-PEG1-OH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs.

NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs.

Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cereblon ligand and a linker[1].

Bromo-PEG1-C2-azide, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs.

Boc-NH-C12-NH2 is an alkyl ether-based PROTAC linker suitable for use in PROTAC synthesis.

Cbz-NH-PEG1-CH2COOH, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.

Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.

Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker.

Cbz-NH-PEG1-CH2CH2COOH, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis.

Boc-NH-PEG12-NH2 (NHBoc-PEG12-amine) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a 28-unit polyethylene glycol (PEG) linker with a cleavable bond, frequently used in the production of antibody-drug conjugates (ADCs)[1].

Thalidomide-NH-C10-NH2 hydrochloride, a thalidomide-derived cereblon ligand, facilitates CRBN protein recruitment and, when conjugated with a linker, forms PROTACs [1].

Thalidomide-5-NH-PEG1-NH2 hydrochloride is a Thalidomide-based cereblon ligand designed for CRBN protein recruitment. It facilitates the formation of PROTAC molecules by linking to target protein ligands, such as THAL-SNS-032, via a connector.

NH2-O-C5-COOH (hydrobromide) is an alkyl chain-derived PROteolysis TArgeting Chimera (PROTAC) linker used in PROTAC synthesis [1].

NH2-PEG1-CH2CH2-Boc is a polyethylene glycol (PEG) and alkyl ether-based proteolysis targeting chimeric (PROTAC) linker, frequently used in PROTAC synthesis[1].

Propargyl-PEG1-NH2, a PEG-based PROTAC linker, can be utilized in the synthesis of PROTACs[1].

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

Thalidomide-NH-(CH2)2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.

m-PEG-NH2 (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-Aminooxy-PEG1-C2-NH2 is a polyethylene glycol (PEG)-derived linker compound designed for incorporation into proteolysis targeting chimeras (PROTACs) [1].

Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Fmoc-NH-PEG5-C2-NH2 is a PEG-based linker for PROTACs that joins two essential ligands, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker used for the synthesis of PROTACs [1].

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is an E3 ligase ligand-linker conjugate designed for targeting the EED protein in PROTAC applications[1].

Bromo-PEG1-C2-Boc is a PEG-based linker for PROTACs, which connects two essential ligands necessary for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thalidomide-NH-C4-NH2 TFA (compound 29c) is a conjugate composed of an E3 ligase ligand-linker that integrates a Thalidomide-based cereblon ligand and a linker moiety. This compound is used as a component in PROTAC BRD2 BRD4 degrader-1, a highly potent and selective degrader targeting BET proteins BRD4 and BRD2[1].

Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 9 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC5 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Pomalidomide - linker 4 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Fmoc-NH-PEG1-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for forming PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system in cells.

Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC linker used for the EED-targeted PROTAC [1].

Thalidomide-O-amido-PEG-C2-NH2 is a synthesized conjugate formulation designed as an E3 ligase ligand-linker conjugate, incorporating a cereblon ligand based on Thalidomide and a linker component commonly used in PROTAC technology.

Thalidomide-NH-C8-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate composed of a cereblon ligand derived from Thalidomide and a linker commonly used in PROTAC technology.

Boc-NH-PEG-amine (MW 3400) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

MV-1-NH-Me, an MV-1-derived IAP ligand, connects to an ABL inhibitor through a linker, resulting in the formation of SNIPER[1].

Thalidomide-NH-C8-NH2 is a synthetic conjugate comprising an E3 ligase ligand-linker, which merges a cereblon ligand derived from Thalidomide with a specific linker used in PROTAC technology.

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate, an ADC linker, is a glutathione-cleavable compound used for attaching monoclonal antibodies (mAb) in antibody-drug conjugates (ADCs), specifically referring to the Alkyl-Chain composition of the linker portion of these molecules [1].

Boc-NH-PEG2-C2-NH2 (PROTAC Linker 13) is a PEG-based linker used in PROTAC synthesis, essential for connecting the targeted protein and the E3 ubiquitin ligase to facilitate selective protein degradation[1].

Boc-NH-PEG23-NH2 is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by connecting two essential ligands, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Thalidomide-NH-C6-NH2 TFA is a synthetic conjugate compound that integrates a cereblon ligand derived from Thalidomide with a linker used in PROTAC technology, serving as an E3 ligase ligand-linker conjugate[1].

2-Bromo-22-dimethyl-acetamido-PEG3-acid is a polyethylene glycol (PEG) derivative commonly used as a PEG-based PROTAC linker in PROTAC synthesis [1].

Thalidomide-NH-CBP p300 ligand 2 (P-007) is a PROTAC-based compound engineered to degrade the proteins CBP and p300, functioning as a molecular antagonist (WO2020173440).

NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) is a PEG-based compound used as a linker in the synthesis of PROTACs[1].

Acrylate-PEG-NH2 (MW 2000) is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker used in the synthesis of PROTACs [1].

m-PEG-NH2 (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.