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C-NH-Boc-C-Bis-(C1-PEG1-PFP)

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Catalog No. T14850Cas No. 1807521-01-2

C-NH-Boc-C-Bis-(C1-PEG1-PFP), a polyethylene glycol (PEG)-derived PROTAC linker, is utilized in the synthesis of PROTACs [1].

C-NH-Boc-C-Bis-(C1-PEG1-PFP)

C-NH-Boc-C-Bis-(C1-PEG1-PFP)

😃Good
Catalog No. T14850Cas No. 1807521-01-2
C-NH-Boc-C-Bis-(C1-PEG1-PFP), a polyethylene glycol (PEG)-derived PROTAC linker, is utilized in the synthesis of PROTACs [1].
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Product Introduction

Bioactivity
Description
C-NH-Boc-C-Bis-(C1-PEG1-PFP), a polyethylene glycol (PEG)-derived PROTAC linker, is utilized in the synthesis of PROTACs [1].
In vitro
PROTACs consist of two distinct ligands linked together: one ligand targets an E3 ubiquitin ligase, while the other targets the protein of interest. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Chemical Properties
Molecular Weight667.45
FormulaC26H23F10NO8
Cas No.1807521-01-2
Relative Density.1.456 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

C-NH-Boc-C-Bis-(C1-PEG1-PFP)C NH Boc C Bis (C1 PEG1 PFP)C-NH-Boc-C-Bis-(C-1-PEG1-PFP)CNHBocCBis(C1PEG1PFP)
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