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Calcitetrol

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Catalog No. T19225Cas No. 72203-93-1
Alias 1α, 24, 25-Trihydroxy VD3

Calcitetrol is the hormonally active form of vitamin D with three hydroxyl groups.

Calcitetrol

Calcitetrol

😃Good
Catalog No. T19225Alias 1α, 24, 25-Trihydroxy VD3Cas No. 72203-93-1
Calcitetrol is the hormonally active form of vitamin D with three hydroxyl groups.
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Product Introduction

Bioactivity
Description
Calcitetrol is the hormonally active form of vitamin D with three hydroxyl groups.
In vivo
Calcitriol increases blood calcium levels ([Ca2+]) by promoting absorption of dietary calcium from the gastrointestinal tract and increasing renal tubular reabsorption of calcium, thus reducing the loss of calcium in the urine. Calcitriol also stimulates the release of calcium from bone by its action on the specific type of bone cells referred to as osteoblasts, causing them to release RANKL, which in turn activates osteoclasts.
Alias1α, 24, 25-Trihydroxy VD3
Chemical Properties
Molecular Weight432.64
FormulaC27H44O4
Cas No.72203-93-1
Relative Density.1.10 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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