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CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 (IC50 = 0.23 μM) with little activity at ABCG1. It has been shown to reverse the ABCG2-mediated resistance toward SN 38 and to inhibit ATPase activity.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $213 | 35 days | |
5 mg | $363 | 35 days | |
10 mg | $625 | 35 days | |
25 mg | $1,290 | 35 days |
Description | CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 (IC50 = 0.23 μM) with little activity at ABCG1. It has been shown to reverse the ABCG2-mediated resistance toward SN 38 and to inhibit ATPase activity. |
Alias | CAY10719 |
Molecular Weight | 451.34 |
Formula | C25H20Cl2N2O2 |
Cas No. | 1942919-63-2 |
Relative Density. | 1.372 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMF: 20 mg/mL DMF:PBS(pH7.2) (1:2): 0.33 mg/mL DMSO: 2 mg/mL |
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