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CB30865
🥰Excellent
Catalog No. T14882Cas No. 206275-15-2
Alias ZM-242421, ZM242421, ZM 242421
CB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity.
CB30865
🥰Excellent
Purity: 99.04%
Catalog No. T14882Alias ZM-242421, ZM242421, ZM 242421Cas No. 206275-15-2
CB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $166 | In Stock |
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Purity:99.04%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | CB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity. |
| In vitro | CB30865 showed dramatically increased W1L2 cytotoxicity (EC50=2.8 nM) that was not rescued by precursors or end-products of folate metabolism. CB30865 represents a class of compounds with unique biochemical characteristics such as a delayed, non-phase specific, cell-cycle arrest. [1] CB30865 represents a class of compounds with unique biochemical characteristics such as a delayed, non-phase specific, cell-cycle arrest. [3] |
| Alias | ZM-242421, ZM242421, ZM 242421 |
| Molecular Weight | 516.39 |
| Formula | C26H22BrN5O2 |
| Cas No. | 206275-15-2 |
| Smiles | O=C1N=C(NC2=CC(Br)=C(C=C12)CN(C3=CC=C(C=C3)C(=O)NCC=4C=NC=CC4)CC#C)C |
| Relative Density. | 1.38 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | H2O: < 0.1 mg/mL (insoluble) DMSO: 30 mg/mL (58.10 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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