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Cbl-b-IN-1

Name: Cbl-b-IN-1
Brand: TargetMol
SKU: T37356
Price: 199 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T37356Cas No. 2368841-84-1

Cbl-b-IN-1 is a potent Cbl-b inhibitor (IC50 <100 nM) with potential anticancer activity for the study of intestinal inflammation.

Cbl-b-IN-1

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Purity: 99.68%

Catalog No. T37356Cas No. 2368841-84-1

Cbl-b-IN-1 is a potent Cbl-b inhibitor (IC50 <100 nM) with potential anticancer activity for the study of intestinal inflammation.

Pack Size	Price	Availability	Quantity
1 mg	$199	In Stock

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Purity:99.68%

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COA HNMR LCMS

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Product Introduction

Bioactivity

Description	Cbl-b-IN-1 is a potent Cbl-b inhibitor (IC50 <100 nM) with potential anticancer activity for the study of intestinal inflammation.
Targets&IC50	Cbl-b:<100 nM

Chemical Properties

Molecular Weight	498.631
Formula	C₂₉H₃₄N₆O₂
Cas No.	2368841-84-1
Smiles	Cn1cnnc1CC1(COC1)c1cccc(NC(=O)c2cc(CN3CCC4(CC4)C3)cc(n2)C2CC2)c1

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (100.28 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0055 mL	10.0275 mL	20.0549 mL	100.2746 mL
5 mM	0.4011 mL	2.0055 mL	4.0110 mL	20.0549 mL
10 mM	0.2005 mL	1.0027 mL	2.0055 mL	10.0275 mL
20 mM	0.1003 mL	0.5014 mL	1.0027 mL	5.0137 mL
50 mM	0.0401 mL	0.2005 mL	0.4011 mL	2.0055 mL
100 mM	0.0201 mL	0.1003 mL	0.2005 mL	1.0027 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Cbl-b-IN-1Cbl b IN 1CblbIN1