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Jedi2 is a Piezo1 activator rather than a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a K d of 2770 μM [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $33 | In Stock | |
5 mg | $76 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $249 | In Stock | |
50 mg | $488 | In Stock | |
100 mg | $698 | In Stock | |
1 mL x 10 mM (in DMSO) | $84 | In Stock |
Description | Jedi2 is a Piezo1 activator rather than a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a K d of 2770 μM [1]. |
In vitro | Jedi2 triggers a Piezo1-mediated Ca2+ influx, inducing dose-dependent reactions uniquely in cells transfected with mPiezo1 at a concentration of 200 μM, without affecting cells transfected with mPiezo2 or the vector alone [1]. Similarly, at 1 mM, Jedi2 enhances Ca2+ levels in mCherry-positive HEK293T cells harboring the mPiezo1-mCherry construct, comparable to the response driven by Yoda1 at 30 μM [1]. |
Molecular Weight | 208.23 |
Formula | C10H8O3S |
Cas No. | 651005-90-2 |
Smiles | Cc1oc(cc1C(O)=O)-c1cccs1 |
Relative Density. | 1.336 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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