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Cyclamic acid

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Purity:99.92%

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COA HNMR HPLC

Cyclamic acid

Catalog No. T0941Cas No. 100-88-9

Cyclamic acid (NSC-220327) is an artificial sweetening agent, usually employed as Na or Ca salt (cyclamate). Use suspended in some countries, including USA, because of possible weak carcinogenic activity (disputed).

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Pack Size	Price	Availability
500 mg	$40	In Stock
1 g	$64	In Stock
5 g	$155	In Stock
1 mL x 10 mM (in DMSO)	$44	In Stock

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Product Introduction

Bioactivity

Description	Cyclamic acid (NSC-220327) is an artificial sweetening agent, usually employed as Na or Ca salt (cyclamate). Use suspended in some countries, including USA, because of possible weak carcinogenic activity (disputed).
In vitro	Cyclamic acid in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners in food and pharmaceuticals. Cyclamic acid is in use in more than 50 countries, especially in combination with other sweeteners, to eliminate aftertaste. However, the petition on Cyclamic acid, calcium and sodium cyclamate is being held in abeyance with the FDA in the USA (CFSAN - Office of Food Additive Safety, 2006).
Alias	Cyclamate, NSC 220327, Cyclohexylsulfamic acid

Chemical Properties

Molecular Weight	179.24
Formula	C6H13NO3S
Cas No.	100-88-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/mL (306.87 mM)

Ethanol: 34 mg/mL (189.7 mM)

H2O: 33 mg/mL (184.1 mM)

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	5.5791 mL	27.8956 mL	55.7911 mL	278.9556 mL
5 mM	1.1158 mL	5.5791 mL	11.1582 mL	55.7911 mL
10 mM	0.5579 mL	2.7896 mL	5.5791 mL	27.8956 mL
20 mM	0.2790 mL	1.3948 mL	2.7896 mL	13.9478 mL
50 mM	0.1116 mL	0.5579 mL	1.1158 mL	5.5791 mL
100 mM	0.0558 mL	0.2790 mL	0.5579 mL	2.7896 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NSC220327inhibitsweetenerNSC-220327InhibitorCyclamic acidartificial