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CYM-5478
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Catalog No. T27107Cas No. 870762-83-7
Alias CYM5478, CYM 5478
CYM-5478 is a potent and selective S1P2 agonist that significantly increases the viability of C6 cells in a dose-dependent manner at concentrations above 100 nM under nutrient-deprivation stress (produced by serum-starvation).
CYM-5478
😃Good
Catalog No. T27107Alias CYM5478, CYM 5478Cas No. 870762-83-7
CYM-5478 is a potent and selective S1P2 agonist that significantly increases the viability of C6 cells in a dose-dependent manner at concentrations above 100 nM under nutrient-deprivation stress (produced by serum-starvation).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $233 | 35 days | |
| 5 mg | $987 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | CYM-5478 is a potent and selective S1P2 agonist that significantly increases the viability of C6 cells in a dose-dependent manner at concentrations above 100 nM under nutrient-deprivation stress (produced by serum-starvation). |
| Targets&IC50 | S1PR3:1950 nM (EC50), S1PR4:>10 μM (EC50), S1PR2:119 nM (EC50), S1PR1:1690 nM (EC50), S1PR5:>10 μM (IC50) |
| Alias | CYM5478, CYM 5478 |
| Molecular Weight | 388.38 |
| Formula | C21H19F3N2O2 |
| Cas No. | 870762-83-7 |
| Relative Density. | 1.23 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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