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D-erythro-MAPP

Name: D-erythro-MAPP
Brand: TargetMol
SKU: T37056
Price: 64 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T37056Cas No. 143492-38-0

Alias D-e-MAPP

D-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, a ceramide analog with potential anticancer activity.

D-erythro-MAPP

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Catalog No. T37056Alias D-e-MAPPCas No. 143492-38-0

D-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, a ceramide analog with potential anticancer activity.

Pack Size	Price	Availability
500 μg	$30	35 days
1 mg	$45	35 days
5 mg	$175	35 days
10 mg	$294	35 days

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COA

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	D-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, a ceramide analog with potential anticancer activity.
In vitro	In human breast cancer MCF-7 cells, D-erythro-MAPP (24 hours; 3.13-100 μM) can inhibit cell viability[1].
Alias	D-e-MAPP

Chemical Properties

Molecular Weight	361.56
Formula	C₂₃H₃₉NO₂
Cas No.	143492-38-0
Smiles	CCCCCCCCCCCCCC(=O)N[C@H](C)[C@@H](O)c1ccccc1

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 1 mg/mL (2.7 mM), Sonication is recommended.

Ethanol: 16 mg/mL (44.25 mM), Sonication is recommended.

DMF: 16 mg/mL (44.25 mM), Sonication is recommended.

Ethanol:PBS (pH 7.2) (1:2): 0.5 mg/mL

Solution Preparation Table

DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
1 mM	2.7658 mL	13.8290 mL	27.6579 mL	138.2896 mL

Ethanol/DMF

	1mg	5mg	10mg	50mg
5 mM	0.5532 mL	2.7658 mL	5.5316 mL	27.6579 mL
10 mM	0.2766 mL	1.3829 mL	2.7658 mL	13.8290 mL
20 mM	0.1383 mL	0.6914 mL	1.3829 mL	6.9145 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

D-erythro-MAPPD erythro MAPPDerythroMAPP