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Dacomitinib metabolite M2

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Catalog No. T23950Cas No. 1262034-38-7
Alias UNII-SOA52D3NLL, Dacomitinib cysteine conjugate

Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M.

Dacomitinib metabolite M2

Dacomitinib metabolite M2

😃Good
Catalog No. T23950Alias UNII-SOA52D3NLL, Dacomitinib cysteine conjugateCas No. 1262034-38-7
Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M.
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Product Introduction

Bioactivity
Description
Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M.
AliasUNII-SOA52D3NLL, Dacomitinib cysteine conjugate
Chemical Properties
Molecular Weight591.1
FormulaC27H32ClFN6O4S
Cas No.1262034-38-7
Relative Density.1.412 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

Dacomitinib metabolite M-2Dacomitinib metabolite M2
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