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dAURK-4 hydrochloride
🥰Excellent
Catalog No. T74100
Alias dAURK-4 hydrochloride (2705844-81-9 free base)
dAURK-4 hydrochloride is a selective AURKA (Aurora A) degrader with anticancer and antiproliferative activities. dAURK-4 hydrochloride has been shown to be an anticancer and antiproliferative agent.
dAURK-4 hydrochloride
🥰Excellent
Purity: 99.44%
Catalog No. T74100Alias dAURK-4 hydrochloride (2705844-81-9 free base)
dAURK-4 hydrochloride is a selective AURKA (Aurora A) degrader with anticancer and antiproliferative activities. dAURK-4 hydrochloride has been shown to be an anticancer and antiproliferative agent.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $132 | In Stock |
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CitedSelect Batch
Purity:99.44%
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Product Introduction
Bioactivity
Chemical Properties
| Description | dAURK-4 hydrochloride is a selective AURKA (Aurora A) degrader with anticancer and antiproliferative activities. dAURK-4 hydrochloride has been shown to be an anticancer and antiproliferative agent. |
| In vitro | In MM.1S cells, dAURK-4 hydrochloride (125 nM, 250 nM, 500 nM, 1000 nM; 4 hours or 24 hours) inhibited the protein level of AURKA (Aurora A)[1]. |
| Alias | dAURK-4 hydrochloride (2705844-81-9 free base) |
| Molecular Weight | 1071.93 |
| Formula | C52H53Cl2FN8O12 |
| Smiles | O=C(C1=CC=C(NC2=NC(C3=C(C(C4=C(OC)C=CC=C4F)=NC5)C=C(Cl)C=C3)=C5C=N2)C=C1OC)NCCCOCCOCCOCCCNC(COC6=CC=CC(C(N7C8C(NC(CC8)=O)=O)=O)=C6C7=O)=O.Cl |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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