Shopping Cart
- Remove All
- Your shopping cart is currently empty
DBCO-NHCO-PEG6-Biotin is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the creation of PROTAC molecules. This linker promotes selective protein degradation by utilizing the ubiquitin-proteasome system [within cells].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | DBCO-NHCO-PEG6-Biotin is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the creation of PROTAC molecules. This linker promotes selective protein degradation by utilizing the ubiquitin-proteasome system [within cells]. |
In vitro | PROTACs (Proteolysis Targeting Chimeras) are composed of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, while the other targets the desired protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade the target proteins[1]. |
Molecular Weight | 838.02 |
Formula | C43H59N5O10S |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.