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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | DBCO-PEG9-NH-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 844 |
Formula | C44H65N3O13 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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