dbco-peg-9-nh-boc

DBCO-PEG9-NH-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NH-bis(C1-Boc) is an uncleavable linker used for antibody-drug conjugates (ADC).

NH2-C2-NH-Boc (PROTAC Linker 22), an alkyl chain-based PROTAC linker, can be used in the synthesis of PROTACs.

NH2-C4-NH-Boc (compound 15) is a PROTAC linker of the Alkyl ether class, suitable for synthesizing various PROTAC molecules.

Boc-NH-PEG4-CH2COOH is a cleavable ADC linker utilized in the development of antibody-drug conjugates (ADC)[1].

NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].

NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs.

Boc-NH-PEG1-OH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs.

Boc-NH-PEG7-Tos (t-Boc-N-Amido-PEG7-Tos) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Thalidomide-NH-C4-NH-Boc is a synthesized conjugate used in PROTAC technology, combining a Thalidomide-based cereblon ligand with a linker.

Boc-NH-PEG3-CH2COOH, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis [1].

Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker employed in PROTAC synthesis.

Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Boc-NH-PEG11-OH, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.

Boc-NH-C12-NH2 is an alkyl ether-based PROTAC linker suitable for use in PROTAC synthesis.

Boc-NH-O-C1-NHS ester, an alkyl ether-based PROTAC linker, is utilized in PROTAC synthesis.

Boc-NH-PEG8-CH2CH2NH2 is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative featuring a hydroxyl group and a Boc-protected amino group, used as a PROTAC linker.

Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker.

Boc-NH-PEG12-NH2 (NHBoc-PEG12-amine) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Boc-NH-PEG3-NHS ester is a PEG-based linker utilized in the synthesis of PROTACs.

Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Boc-NH-C4-acid is a PROTAC linker of the Alkyl ether class, utilized in the synthesis of PROTAC1 for the degradation of EED, EZH2, and SUZ12 in [PRC2].

Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).

Boc-NH-PEG4-CH2CH2NH2 is a cleavable 5-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Boc-NH-PEG4-C2-Boc is a PEG-based linker for PROTACs, crucial for uniting two essential ligands and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC linker used for the EED-targeted PROTAC [1].

Tos-PEG2-NH-Boc is a PEG-based linker for PROTACs that joins two essential ligands to form PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Boc-NH-PEG24-CH2CH2COOH is a polyethylene glycol (PEG)-based linker used in the synthesis of PROTAC (Proteolysis-Targeting Chimeras) [1].

Boc-NH-ethyl-SS-propionic acid, an ADC linker compound, is utilized for the synthesis of antibody-drug conjugates (ADCs)[1].

Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTAC[1] and as a cleavable ADC linker for antibody-drug conjugates (ADC)[2].

Tetrazine-Ph-NHCO-PEG4-NH-Boc is a PEGylated PROTAC linker suitable for PROTAC synthesis [1].

Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based linker utilized in the synthesis of PROTACs[1].

Mal-C4-NH-Boc is a alkyl ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG-amine (MW 3400) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

Boc-NH-PEG20-CH2CH2COOH, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1].

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a polyethylene glycol (PEG)-based linker used in the development of proteolysis targeting chimeras (PROTACs)[1].

Boc-NH-PEG8-propargyl, a PEG-based linker for PROTACs, joins two essential ligands to form PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].

Boc-NH-PEG2-CH2CH2COOH is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG3-propargyl is a PEG-based linker used in PROTACs for connecting two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Fmoc-N-bis-PEG3-NH-Boc is a cleavable ADC linker compound with three PEG units, used in the synthesis of antibody-drug conjugates (ADCs)[1].

Methyltetrazine-PEG4-NH-Boc is a PEGylation-based linker used for synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is an E3 ligase ligand-linker conjugate designed for targeting the EED protein in PROTAC applications[1].

Mal-NH-Boc is a alkyl ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG10-CH2CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker used in PROTAC synthesis [1].