Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Demethylisoencecalin

🥰Excellent
Catalog No. TN6793Cas No. 24672-84-2
Alias 6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran

Demethylisoencecalin (6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran) has anti-hyperglycemic activity.

Demethylisoencecalin

Demethylisoencecalin

🥰Excellent
Purity: 99.89%
Catalog No. TN6793Alias 6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyranCas No. 24672-84-2
Demethylisoencecalin (6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran) has anti-hyperglycemic activity.
Pack SizePriceAvailabilityQuantity
1 mg103 â‚¬In Stock
5 mg254 â‚¬In Stock
10 mg372 â‚¬In Stock
25 mg634 â‚¬In Stock
50 mg901 â‚¬In Stock
1 mL x 10 mM (in DMSO)266 â‚¬In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "Demethylisoencecalin"

Select Batch
Purity:99.89%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Demethylisoencecalin (6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran) has anti-hyperglycemic activity.
In vitro
Demethylisoencecalin (1) and caleins A (4) and C (5) (3.16–31.6 mg/kg, p.o.), the major components from an infusion of Calea ternifolia controlled postprandial glucose levels during an oral sucrose tolerance test (OSTT, 3 g/kg) in normal and nicotinamide/streptozotocin (NA/STZ, 40/100 mg/kg) hyperglicemic mice. The effects were comparable to those of acarbose (5 mg/kg). During the isolation of 1, 4, and 5, four additional metabolites not previously reported for the plant, were obtained, namely 6-acetyl-5-hydroxy-2-methyl-2-hydroxymethyl-2H-chromene (3), herniarin (6), scoparone (7), and 4′,7-dimethylapigenin (8). In addition, the structure of calein C (5) was confirmed by X-ray analysis. Pharmacological evaluation of the essential oil of the species (31.6–316.2 mg/kg, p.o.) provoked also an important decrement of blood glucose levels during an OSTT[1].
Alias6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran
Chemical Properties
Molecular Weight218.25
FormulaC13H14O3
Cas No.24672-84-2
SmilesOC1=C2C(OC(C)(C)C=C2)=CC=C1C(C)=O
Relative Density.1.154 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/ml (274.91 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.5819 mL22.9095 mL45.8190 mL229.0951 mL
5 mM0.9164 mL4.5819 mL9.1638 mL45.8190 mL
10 mM0.4582 mL2.2910 mL4.5819 mL22.9095 mL
20 mM0.2291 mL1.1455 mL2.2910 mL11.4548 mL
50 mM0.0916 mL0.4582 mL0.9164 mL4.5819 mL
100 mM0.0458 mL0.2291 mL0.4582 mL2.2910 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Demethylisoencecalin | purchase Demethylisoencecalin | Demethylisoencecalin cost | order Demethylisoencecalin | Demethylisoencecalin chemical structure | Demethylisoencecalin in vitro | Demethylisoencecalin formula | Demethylisoencecalin molecular weight