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Dichloro(1,2-diaminocyclohexane)platinum(II)

Name: Dichloro(1,2-diaminocyclohexane)platinum(II)
Brand: TargetMol
SKU: T201906
Rating: 4.5 (1 reviews)

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Catalog No. T201906Cas No. 52691-24-4

Alias Dichloro-1,2-diaminocyclohexane platinum complex

Dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt) is a platinum compound with potential anti-cancer activity, used for studying bacterial infections and cancer.

Dichloro(1,2-diaminocyclohexane)platinum(II)

🥰Excellent

Catalog No. T201906Alias Dichloro-1,2-diaminocyclohexane platinum complexCas No. 52691-24-4

Dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt) is a platinum compound with potential anti-cancer activity, used for studying bacterial infections and cancer.

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Product Introduction

Bioactivity

Description	Dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt) is a platinum compound with potential anti-cancer activity, used for studying bacterial infections and cancer.
In vitro	Dichloro(1,2-diaminocyclohexane)platinum complex showed increased uptake of Pt (II) by cells. [1]
In vivo	The polymer micelle of Dichloro(1,2-diaminocyclohexane)platinum complex (4 mg/kg) was treated with A2780 human ovarian cancer xenografts in mice and significantly inhibited tumor growth. [1] Polymer micelles of Dichloro(1,2-diaminocyclohexane)platinum complex (4 mg/kg) inhibited tumor growth and lymph node metastasis in mice with in-situ sachycephalic gastric tumors. [2]
Alias	Dichloro-1,2-diaminocyclohexane platinum complex

Chemical Properties

Molecular Weight	380.18
Formula	C₆H₁₄Cl₂N₂Pt
Cas No.	52691-24-4
Smiles	[Cl-][Pt+2]1([Cl-])[NH2]C2CCCCC2[NH2]1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

dichloro1,2diaminocyclohexaneplatinumcomplex

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