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DO3A tert-Butyl ester

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DO3A tert-Butyl ester

Catalog No. T19293Cas No. 122555-91-3

DOTA tert-butyl ester is a phenyl derivative of cycloteramide; it can be directly nitrated; it is more convenient to add nitro after deprotection of lithium aluminum hydride.

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Pack Size	Price	Availability
10 mg	$34	7-10 days
25 mg	$69	7-10 days
1 mL x 10 mM (in DMSO)	$129	7-10 days

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Product Introduction

Bioactivity

Description	DOTA tert-butyl ester is a phenyl derivative of cycloteramide; it can be directly nitrated; it is more convenient to add nitro after deprotection of lithium aluminum hydride.
Alias	DO3A-t-Bu-ester, DO3A tert-butyl

Chemical Properties

Molecular Weight	514.7
Formula	C26H50N4O6
Cas No.	122555-91-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 125 mg/mL (242.86 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9429 mL	9.7144 mL	19.4288 mL	97.1440 mL
5 mM	0.3886 mL	1.9429 mL	3.8858 mL	19.4288 mL
10 mM	0.1943 mL	0.9714 mL	1.9429 mL	9.7144 mL
20 mM	0.0971 mL	0.4857 mL	0.9714 mL	4.8572 mL
50 mM	0.0389 mL	0.1943 mL	0.3886 mL	1.9429 mL
100 mM	0.0194 mL	0.0971 mL	0.1943 mL	0.9714 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DO3A tert Butyl esterDO3A tert-Butyl esterDO3A tertButyl esterDO-3A tert-Butyl ester