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EGFR-IN-45

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Catalog No. T63070

EGFR-IN-45 is a potent pan-inhibitor of the epidermal growth factor receptor (EGFR) with an IC50 of 0.4 μM and also targets CDK2 with an IC50 of 1.6 μM. It inhibits topoisomerases Topo I and Topo II, blocks the cancer cell cycle in the pre-G1 phase, and induces apoptosis.

EGFR-IN-45

EGFR-IN-45

😃Good
Catalog No. T63070
EGFR-IN-45 is a potent pan-inhibitor of the epidermal growth factor receptor (EGFR) with an IC50 of 0.4 μM and also targets CDK2 with an IC50 of 1.6 μM. It inhibits topoisomerases Topo I and Topo II, blocks the cancer cell cycle in the pre-G1 phase, and induces apoptosis.
Pack SizePriceAvailabilityQuantity
25 mg$1,520 10-14 weeks
50 mg$1,980 10-14 weeks
100 mg$2,500 10-14 weeks
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Product Introduction

Bioactivity
Description
EGFR-IN-45 is a potent pan-inhibitor of the epidermal growth factor receptor (EGFR) with an IC50 of 0.4 μM and also targets CDK2 with an IC50 of 1.6 μM. It inhibits topoisomerases Topo I and Topo II, blocks the cancer cell cycle in the pre-G1 phase, and induces apoptosis.
Chemical Properties
Molecular Weight473.53
FormulaC28H23N7O
Storage & Solubility Information
StorageShipping with blue ice.

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