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Emapalumab
🥰Excellent
Catalog No. T76742Cas No. 1709815-23-5
Alias NI-0501
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-γ and to IFN-γ bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH).
Emapalumab
Emapalumab
🥰Excellent
Purity: 97.56% (SEC-HPLC)
Catalog No. T76742Alias NI-0501Cas No. 1709815-23-5
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-γ and to IFN-γ bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $238 | In Stock | |
| 5 mg | $639 | In Stock | |
| 10 mg | $891 | In Stock | |
| 25 mg | $1,370 | In Stock | |
| 50 mg | $1,830 | In Stock | |
| 100 mg | $2,490 | In Stock |
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CitedSelect Batch
Concentration:9.24 mg/mL
Purity:97.56% (SEC-HPLC)
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Product Introduction
Bioactivity
Chemical Properties
| Description | Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-γ and to IFN-γ bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH). |
| In vitro | Impaired by Emapalumab (NI-0501) is the interaction between IFNcR1 and IFNc-Receptor-2 (IFNcR2) induced by IFNc at the cell surface. |
| Alias | NI-0501 |
| Molecular Weight | 145.22 kDa |
| Cas No. | 1709815-23-5 |
Storage & Solubility Information
| Storage | store at low temperature | store at -80°C | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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