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Esomeprazole potassium salt

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Catalog No. T61667Cas No. 161796-84-5

Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is an effective and orally active proton pump inhibitor that inhibits H+, K+-ATPase enzyme in gastric parietal cells, reducing acid secretion. It is a promising compound for investigating symptomatic gastroesophageal reflux disease [1] [2] [3].

Esomeprazole potassium salt
Other Forms of Esomeprazole potassium salt:

Esomeprazole potassium salt

😃Good
Catalog No. T61667Cas No. 161796-84-5
Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is an effective and orally active proton pump inhibitor that inhibits H+, K+-ATPase enzyme in gastric parietal cells, reducing acid secretion. It is a promising compound for investigating symptomatic gastroesophageal reflux disease [1] [2] [3].
Pack SizePriceAvailabilityQuantity
25 mg$1,5201-2 weeks
50 mg$1,9801-2 weeks
100 mg$2,5001-2 weeks
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Product Introduction

Bioactivity
Description
Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is an effective and orally active proton pump inhibitor that inhibits H+, K+-ATPase enzyme in gastric parietal cells, reducing acid secretion. It is a promising compound for investigating symptomatic gastroesophageal reflux disease [1] [2] [3].
In vitro
Esomeprazole (25-100 μM; 20 hours; MDA-MB-468 cells) treatment suppresses the growth of triple-negative breast cancer cells in vitro in a dose-dependent manner through increased intracellular acidification [1].
In vivo
Esomeprazole (30-300 mg/kg; oral gavage; daily; for 19 or 11 days; C57BL/6J mice) significantly inhibits lung fibrosis progression and reduces circulating markers of inflammation and fibrosis [2]. Animal Model: C57BL/6J mice (8-weeks old, 25-30 g) with cotton smoke-induced lung injury [2].
Chemical Properties
Molecular Weight383.51
FormulaC17H18KN3O3S
Cas No.161796-84-5
Storage & Solubility Information
StorageShipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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