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Ferroportin-IN-1

🥰Excellent
Catalog No. T62954Cas No. 2443432-65-1

Ferroportin-IN-1 is an inhibitor of the iron transport protein Ferroportin, which regulates cellular iron efflux and metabolism to study diseases caused by iron-modulating deficiencies or disorders of iron metabolism, used in metabolism studies such as thalassemia, sickle cell disease, and hemochromatosis.

Ferroportin-IN-1

Ferroportin-IN-1

🥰Excellent
Purity: 99.85%
Catalog No. T62954Cas No. 2443432-65-1
Ferroportin-IN-1 is an inhibitor of the iron transport protein Ferroportin, which regulates cellular iron efflux and metabolism to study diseases caused by iron-modulating deficiencies or disorders of iron metabolism, used in metabolism studies such as thalassemia, sickle cell disease, and hemochromatosis.
Pack SizePriceAvailabilityQuantity
1 mg$293 In Stock
5 mg$722 In Stock
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Purity:99.85%
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COA FNMR HNMR HPLC LCMS
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Product Introduction

Bioactivity
Description
Ferroportin-IN-1 is an inhibitor of the iron transport protein Ferroportin, which regulates cellular iron efflux and metabolism to study diseases caused by iron-modulating deficiencies or disorders of iron metabolism, used in metabolism studies such as thalassemia, sickle cell disease, and hemochromatosis.
Chemical Properties
Molecular Weight464.52
FormulaC22H21FN8OS
Cas No.2443432-65-1
SmilesO=C1N=C(NCC2=NC=CC=C2F)C=3N=C(SC3N1)CCNCCC4=NC=5C=CC=CC5N4
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (172.22 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1528 mL10.7638 mL21.5276 mL107.6380 mL
5 mM0.4306 mL2.1528 mL4.3055 mL21.5276 mL
10 mM0.2153 mL1.0764 mL2.1528 mL10.7638 mL
20 mM0.1076 mL0.5382 mL1.0764 mL5.3819 mL
50 mM0.0431 mL0.2153 mL0.4306 mL2.1528 mL
100 mM0.0215 mL0.1076 mL0.2153 mL1.0764 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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