Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FGFR1 inhibitor-2 (with an IC50 of 4.55 μM in MDA-MB-231 cells) is a potent inhibitor of FGFR1. It is specifically useful for studying metastatic triple-negative breast cancer.
Pack Size | Availability | Price/USD | Quantity |
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5 mg | Inquiry | $ 970.00 |
Description | FGFR1 inhibitor-2 (with an IC50 of 4.55 μM in MDA-MB-231 cells) is a potent inhibitor of FGFR1. It is specifically useful for studying metastatic triple-negative breast cancer. |
In vitro | FGFR1 inhibitor-2, when applied at concentrations of 3 and 6 μM to MDA-MB-231 cells for a duration of 48 hours, effectively diminishes FGFR1 expression, as evidenced by Western Blot Analysis[1]. Additionally, a dose-dependent increase in the apoptotic index of MDA-MB-231 cells is observed, reaching a significant 10.6-fold elevation at a concentration of 5 μM, indicating a pronounced pro-apoptotic effect at this dosage[1]. |
Synonyms | FGFR1 inhibitor-2 |
Molecular Weight | 507.461 |
Formula | C25H22F5N3O3 |
CAS No. | 2410612-08-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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FGFR1 inhibitor-2 2410612-08-5 FGFR1 inhibitor 2 FGFR1 inhibitor2 FGFR-1 inhibitor-2 inhibitor inhibit