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FGFR4-IN-10

Catalog No. T62682

FGFR4-IN-10 (compound 5a) is a selective and potent FGFR4 inhibitor (IC50: 70.7 nM) and does not inhibit other FGFR family members (i.e., FGFR1, FGFR2, and FGFR3).

FGFR4-IN-10

FGFR4-IN-10

Catalog No. T62682
FGFR4-IN-10 (compound 5a) is a selective and potent FGFR4 inhibitor (IC50: 70.7 nM) and does not inhibit other FGFR family members (i.e., FGFR1, FGFR2, and FGFR3).
Pack SizePriceAvailabilityQuantity
25 mg$1,52010-14 weeks
50 mg$1,98010-14 weeks
100 mg$2,50010-14 weeks
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Product Introduction

Bioactivity
Description
FGFR4-IN-10 (compound 5a) is a selective and potent FGFR4 inhibitor (IC50: 70.7 nM) and does not inhibit other FGFR family members (i.e., FGFR1, FGFR2, and FGFR3).
Chemical Properties
Molecular Weight448.4
FormulaC20H19F3N6O3
Storage & Solubility Information
StorageShipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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