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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $32 | 5 days | |
5 mg | $48 | 5 days |
Description | Fmoc-NMe-PEG4-C2-acid, a PEG-based linker for PROTACs, connects two essential ligands crucial for PROTAC molecule formation and facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs utilize a linker to connect two ligands: one binding to an E3 ubiquitin ligase and the other to the target protein, thereby leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 501.57 |
Formula | C27H35NO8 |
Cas No. | 2170240-98-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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