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Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester serves as a cleavable 4-unit PEG-based ADC linker in the formulation of antibody-drug conjugates (ADCs) [1]. This compound acts as a click chemistry agent featuring an Azide group, enabling it to engage in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-bearing molecules. Additionally, it facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules equipped with DBCO or BCN groups.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester serves as a cleavable 4-unit PEG-based ADC linker in the formulation of antibody-drug conjugates (ADCs) [1]. This compound acts as a click chemistry agent featuring an Azide group, enabling it to engage in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-bearing molecules. Additionally, it facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules equipped with DBCO or BCN groups. |
Molecular Weight | 807.76 |
Formula | C38H42F5N5O9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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