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Fotemustine

🥰Excellent
Catalog No. T21305Cas No. 92118-27-9

Fotemustine is a chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates DNA in cells, resulting in inhibition of DNA synthesis, cell cycle arrest, and finally apoptosis. This agent is lipophilic and crosses the blood-brain barrier.

Fotemustine

Fotemustine

🥰Excellent
Catalog No. T21305Cas No. 92118-27-9
Fotemustine is a chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates DNA in cells, resulting in inhibition of DNA synthesis, cell cycle arrest, and finally apoptosis. This agent is lipophilic and crosses the blood-brain barrier.
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Product Introduction

Bioactivity
Description
Fotemustine is a chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates DNA in cells, resulting in inhibition of DNA synthesis, cell cycle arrest, and finally apoptosis. This agent is lipophilic and crosses the blood-brain barrie
Chemical Properties
Molecular Weight315.69
FormulaC9H19ClN3O5P
Cas No.92118-27-9
Relative Density.1.37 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: Soluble
H2O: Insoluble

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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