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FSG67
🥰Excellent
Catalog No. T60926Cas No. 1158383-34-6
Alias FSG 67
FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) and glycerol-3-phosphate acyltransferase, mitochondrial (GPAM) inhibitor that attenuates hepatic regeneration following acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling.
FSG67
🥰Excellent
Catalog No. T60926Alias FSG 67Cas No. 1158383-34-6
FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) and glycerol-3-phosphate acyltransferase, mitochondrial (GPAM) inhibitor that attenuates hepatic regeneration following acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $305 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) and glycerol-3-phosphate acyltransferase, mitochondrial (GPAM) inhibitor that attenuates hepatic regeneration following acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling. |
| Targets&IC50 | oxidative metabolis:27.7 μM, 3-phosphate acyltransferase (GPAT):24 μM |
| In vitro | FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) inhibitor with an IC50 value of 24 μM.FSG67 was able to reduce the level of phosphorylation of GSK3β and associated signaling after paracetamol (acetaminophen) overdose. [1] In mature adipocytes, FSG67 elevated oxidative metabolism in a dose-dependent manner with an IC50 of 27.7 μM. [2] |
| Alias | FSG 67 |
| Molecular Weight | 327.44 |
| Formula | C16H25NO4S |
| Cas No. | 1158383-34-6 |
| Smiles | O=C(O)C=1C=CC=CC1NS(=O)(=O)CCCCCCCCC |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (244.32 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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