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Gefitinib N-oxide

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Catalog No. T11385Cas No. 847949-51-3

Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib N-oxide is the N-oxide derivative of Gefitinib.

Gefitinib N-oxide
Other Forms of Gefitinib N-oxide:
Gefitinib N-oxide hydrochlorideT73627
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Gefitinib N-oxide

😃Good
Catalog No. T11385Cas No. 847949-51-3
Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib N-oxide is the N-oxide derivative of Gefitinib.
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib N-oxide is the N-oxide derivative of Gefitinib.
Targets&IC50
Tyr992 site (NR6wtEGFR cells):37 nM , Tyr1173 site (NR6wtEGFR cells):37 nM
Chemical Properties
Molecular Weight462.9
FormulaC22H24ClFN4O4
Cas No.847949-51-3
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

Tyr992 site, in NR6wtEGFR cellsTyr1173 site, in NR6wtEGFR cellsGefitinib N-oxideGefitinib NoxideGefitinib N oxide
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