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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $330 | 35 days | |
5 mg | $1,190 | 35 days |
Description | Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal administration of glucagon in humanized mice. Glucagon receptor antagonist inactive control does not prevent glucagon-mediated actions. |
Molecular Weight | 346.53 |
Formula | C20H30N2OS |
Cas No. | 438618-32-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: Soluble |
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