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GNE-7915 tosylate

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Catalog No. T72640Cas No. 2070015-00-6

GNE-7915 (tosylate) is a potent, selective, and brain-penetrant LRRK2 inhibitor with an IC50 value of 9 nM.

GNE-7915 tosylate

GNE-7915 tosylate

😃Good
Catalog No. T72640Cas No. 2070015-00-6
GNE-7915 (tosylate) is a potent, selective, and brain-penetrant LRRK2 inhibitor with an IC50 value of 9 nM.
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100 mgInquiry1-2 weeks
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Product Introduction

Bioactivity
Description
GNE-7915 (tosylate) is a potent, selective, and brain-penetrant LRRK2 inhibitor with an IC50 value of 9 nM.
Chemical Properties
Molecular Weight615.6
FormulaC26H29F4N5O6S
Cas No.2070015-00-6
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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