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Hexadimethrine bromide

Catalog No. T13720Cas No. 28728-55-4
Alias Polybrene, 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide

Hexadimethrine bromide (1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide) is a synthetic polymer which agglutinates red blood cells, and used as a heparin antagonist.

Hexadimethrine bromide

Hexadimethrine bromide

Catalog No. T13720Alias Polybrene, 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromideCas No. 28728-55-4
Hexadimethrine bromide (1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide) is a synthetic polymer which agglutinates red blood cells, and used as a heparin antagonist.
Pack SizePriceAvailabilityQuantity
50 mg$41In Stock
100 mg$66In Stock
200 mg$94In Stock
500 mg$158In Stock
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Purity:≥98%
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Product Introduction

Bioactivity
Description
Hexadimethrine bromide (1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide) is a synthetic polymer which agglutinates red blood cells, and used as a heparin antagonist.
In vitro
Hexadimethrine bromide impedes the proliferation of human mesenchymal stem cells during lentiviral transduction and is deemed non-toxic at low concentrations. Yet, at levels exceeding 10 µg/mL, it adversely impacts the proliferation of certain cell types. Moreover, cells treated with Hexadimethrine bromide and then trypsinized appear significantly enlarged under microscopic examination.
AliasPolybrene, 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide
Chemical Properties
Formula(C13H30N2)n.Br2
Cas No.28728-55-4
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.5 mg/mL, Sonication and heating are recommended.
H2O: 125 mg/mL (309.20 mM)

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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