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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $970 | 1-2 weeks |
Description | HM03 trihydrochloride, a potent and selective inhibitor of HSPA5 (also known as Bip or Grp78), exhibits anticancer activity. |
In vitro | HM03 trihydrochloride, at concentrations ranging from 0.1-50 μM and applied over 72 hours, demonstrates significant inhibitory activity, achieving over 50% inhibition at a 25 μM concentration in HCT116 cells[1]. It preferentially interacts with HSPA5 and HSPA9, forming more binding interactions compared to other HSP70 proteins. This compound has shown promising results in assays evaluating cancer cell viability and tumor inhibition[1]. |
Molecular Weight | 572.35 |
Formula | C26H30Cl4N4O2 |
Cas No. | 1082532-95-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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