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IDO-IN-8

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Catalog No. T11621Cas No. 1402837-77-7
Alias NLG-1487

IDO-IN-8 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM).

IDO-IN-8

IDO-IN-8

😃Good
Catalog No. T11621Alias NLG-1487Cas No. 1402837-77-7
IDO-IN-8 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM).
Pack SizePriceAvailabilityQuantity
10 mg1.130 €6-8 weeks
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Product Introduction

Bioactivity
Description
IDO-IN-8 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM).
Targets&IC50
IDO:1-10 μM
In vitro
IDO-IN-8 is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 1-10 μM (this is the concentration of IDO-IN-8 at which inhibits 50% of enzymatic activity using recombinant human IDO).
AliasNLG-1487
Chemical Properties
Molecular Weight316.37
FormulaC18H21FN2O2
Cas No.1402837-77-7
Relative Density.1.42 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 100 mg/mL (316.09 mM), Sonication is recommended.
Solution Preparation Table
Ethanol
1mg5mg10mg50mg
1 mM3.1609 mL15.8043 mL31.6086 mL158.0428 mL
5 mM0.6322 mL3.1609 mL6.3217 mL31.6086 mL
10 mM0.3161 mL1.5804 mL3.1609 mL15.8043 mL
20 mM0.1580 mL0.7902 mL1.5804 mL7.9021 mL
50 mM0.0632 mL0.3161 mL0.6322 mL3.1609 mL
100 mM0.0316 mL0.1580 mL0.3161 mL1.5804 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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