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Ioxilan

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Catalog No. T19377Cas No. 107793-72-6
Alias Oxilan, Imagenil

Ioxilan (Imagenil) is a tri-iodinated X-ray contrast agent used in computer tomography (CECT) imaging as a biological membrane transparency agent.

Ioxilan

Ioxilan

😃Good
Purity: 98.34%
Catalog No. T19377Alias Oxilan, ImagenilCas No. 107793-72-6
Ioxilan (Imagenil) is a tri-iodinated X-ray contrast agent used in computer tomography (CECT) imaging as a biological membrane transparency agent.
Pack SizePriceAvailabilityQuantity
1 mg$99 In Stock
1 mL x 10 mM (in DMSO)$215 8-10 weeks
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Purity:98.34%
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Product Introduction

Bioactivity
Description
Ioxilan (Imagenil) is a tri-iodinated X-ray contrast agent used in computer tomography (CECT) imaging as a biological membrane transparency agent.
In vitro
Ioxilan introduces dimethylene as a hydrophobic region masked by hydrophilic hydroxyl, which can reduce osmotic pressure without adversely affecting biological tolerance, and can improve the safety and tolerance of X-ray contrast agents. [2]
In vivo
Ioxilan increased the excretion of albumin, LDH and GGT in rats, resulting in temporary glomerular and tubular dysfunction in rats, but the effect was less than that of diatrizoate and iohexol. [1]
AliasOxilan, Imagenil
Chemical Properties
Molecular Weight791.11
FormulaC18H24I3N3O8
Cas No.107793-72-6
SmilesO=C(NCCO)C=1C(I)=C(C(=O)NCC(O)CO)C(I)=C(C1I)N(C(=O)C)CC(O)CO
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 200 mg/mL (252.81 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2640 mL6.3202 mL12.6405 mL63.2023 mL
5 mM0.2528 mL1.2640 mL2.5281 mL12.6405 mL
10 mM0.1264 mL0.6320 mL1.2640 mL6.3202 mL
20 mM0.0632 mL0.3160 mL0.6320 mL3.1601 mL
50 mM0.0253 mL0.1264 mL0.2528 mL1.2640 mL
100 mM0.0126 mL0.0632 mL0.1264 mL0.6320 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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