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K-Ras G12C-IN-2

Name: K-Ras G12C-IN-2
Brand: TargetMol
SKU: T11736
Price: 29 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T11736Cas No. 1629267-75-9

K-Ras G12C-IN-2 is a covalent KRAS G12C inhibitor.

K-Ras G12C-IN-2

😃Good

Catalog No. T11736Cas No. 1629267-75-9

K-Ras G12C-IN-2 is a covalent KRAS G12C inhibitor.

Pack Size	Price	Availability
25 mg	$1,820	8-10 weeks
50 mg	$2,380	8-10 weeks
100 mg	$3,100	8-10 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description

K-Ras G12C-IN-2 is a covalent KRAS G12C inhibitor.

Chemical Properties

Molecular Weight	418.92
Formula	C₂₁H₂₇ClN₄O₃
Cas No.	1629267-75-9
Relative Density.	1.393 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 22 mg/mL (52.52 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3871 mL	11.9355 mL	23.8709 mL	119.3545 mL
5 mM	0.4774 mL	2.3871 mL	4.7742 mL	23.8709 mL
10 mM	0.2387 mL	1.1935 mL	2.3871 mL	11.9355 mL
20 mM	0.1194 mL	0.5968 mL	1.1935 mL	5.9677 mL
50 mM	0.0477 mL	0.2387 mL	0.4774 mL	2.3871 mL

Calculator

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Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

K-Ras G-12C-IN-2K Ras G12C IN 2K-Ras G12C-IN-2KRas G12CIN2