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Description | KH-CB20, an E/Z mixture, is a potent and selective inhibitor of CLK1 and CLK4 , with an IC 50 of 16.5 nM for CLK1 . KH-CB20 also can inhibits DYRK1A ( IC 50 =57.8 nM) and CLK3 ( IC 50 =488 nM). |
In vitro | KH-CB20 shows selectivity for CLK1 (IC 50 =16.5 nM) over DYRK1A (IC 50 =57.8 nM) and CLK3 (IC 50 =488 nM)[1]. |
Alias | KH-CB20 |
Molecular Weight | 338.19 |
Formula | C15H13Cl2N3O2 |
Cas No. | 1354448-60-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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