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KRAS inhibitor-14

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Catalog No. T63235Cas No. 2230873-78-4

KRAS inhibitor-14 is a potent inhibitor of KRAS G12C (IC50: 0.249 μM). KRAS inhibitor-14 exhibited p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 1.12, >33.3 μM, respectively. KRAS inhibitor-14 has potential to be investigated in pancreatic, colorectal and lung cancers.

KRAS inhibitor-14

KRAS inhibitor-14

😃Good
Catalog No. T63235Cas No. 2230873-78-4
KRAS inhibitor-14 is a potent inhibitor of KRAS G12C (IC50: 0.249 μM). KRAS inhibitor-14 exhibited p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 1.12, >33.3 μM, respectively. KRAS inhibitor-14 has potential to be investigated in pancreatic, colorectal and lung cancers.
Pack SizePriceAvailabilityQuantity
25 mg$2,1408-10 weeks
50 mg$2,7858-10 weeks
100 mg$3,5208-10 weeks
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Product Introduction

Bioactivity
Description
KRAS inhibitor-14 is a potent inhibitor of KRAS G12C (IC50: 0.249 μM). KRAS inhibitor-14 exhibited p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 1.12, >33.3 μM, respectively. KRAS inhibitor-14 has potential to be investigated in pancreatic, colorectal and lung cancers.
Chemical Properties
Molecular Weight486.77
FormulaC20H15Cl3FN3O2S
Cas No.2230873-78-4
Storage & Solubility Information
StorageShipping with blue ice.

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