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KT182

Catalog No. T11784Cas No. 1402612-62-7

KT182 is a selective and  potent inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells.

KT182

KT182

Purity: 100%
Catalog No. T11784Cas No. 1402612-62-7
KT182 is a selective and  potent inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells.
Pack SizePriceAvailabilityQuantity
1 mg$38In Stock
5 mg$93In Stock
10 mg$143In Stock
25 mg$237In Stock
50 mg$353In Stock
100 mg$495In Stock
500 mg$987In Stock
1 mL x 10 mM (in DMSO)$98In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
KT182 is a selective and  potent inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells.
Targets&IC50
ABHD6 (Neuro2A cells):0.24 nM
In vivo
KT182 (i.p, 1mg/kg, 4 hours) complete blockade of ABHD6 in the mice liver[1].
Chemical Properties
Molecular Weight438.52
FormulaC27H26N4O2
Cas No.1402612-62-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90 mg/mL (205.2 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2804 mL11.4020 mL22.8040 mL114.0199 mL
5 mM0.4561 mL2.2804 mL4.5608 mL22.8040 mL
10 mM0.2280 mL1.1402 mL2.2804 mL11.4020 mL
20 mM0.1140 mL0.5701 mL1.1402 mL5.7010 mL
50 mM0.0456 mL0.2280 mL0.4561 mL2.2804 mL
100 mM0.0228 mL0.1140 mL0.2280 mL1.1402 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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