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L-Homopropargylglycine

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L-Homopropargylglycine

Catalog No. T15694Cas No. 98891-36-2

L-Homopropargylglycine is a methionine analog commonly used in bioorthogonal non-classical amino acid labeling to detect bacterial activity and to detect protein synthesis.

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Pack Size	Price	Availability	Quantity
2 mg	$45	In Stock

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Product Introduction

Bioactivity

Description	L-Homopropargylglycine is a methionine analog commonly used in bioorthogonal non-classical amino acid labeling to detect bacterial activity and to detect protein synthesis.
In vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for the E3 ubiquitin ligase and the other is a ligand for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade the target protein[1].

Chemical Properties

Molecular Weight	127.14
Formula	C6H9NO2
Cas No.	98891-36-2

Storage & Solubility Information

Storage

store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (786.53 mM)

H2O: 60 mg/mL (471.92 mM)

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	7.8653 mL	39.3267 mL	78.6535 mL	393.2673 mL
5 mM	1.5731 mL	7.8653 mL	15.7307 mL	78.6535 mL
10 mM	0.7865 mL	3.9327 mL	7.8653 mL	39.3267 mL
20 mM	0.3933 mL	1.9663 mL	3.9327 mL	19.6634 mL
50 mM	0.1573 mL	0.7865 mL	1.5731 mL	7.8653 mL
100 mM	0.0787 mL	0.3933 mL	0.7865 mL	3.9327 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

LHomopropargylglycineL-HomopropargylglycineL Homopropargylglycine