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Lucigenin

Name: Lucigenin
Brand: TargetMol
SKU: T19023
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19023Cas No. 2315-97-1

Alias NSC-151912, L-6868

Lucigenin (NSC-151912) (L-6868) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells.

Lucigenin

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Purity: 99.42%

Catalog No. T19023Alias NSC-151912, L-6868Cas No. 2315-97-1

Lucigenin (NSC-151912) (L-6868) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells.

Pack Size	Price	Availability	Quantity
50 mg	$29	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Purity:99.42%

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COA HPLC HNMR

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Product Introduction

Bioactivity

Description	Lucigenin (NSC-151912) (L-6868) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells.
In vitro	Upon single-electron reduction of Lucigenin by a radical species the subsequent form of Lucigenin presents amplified chemiluminescence which is measurable and can be correlated to the respective amount of reactive radical species present in the system. In addition to indicating the presence of radicals in cells, Lucigenin shows interaction with redox-active oxidoreductase enzymes. Lucigenin is shown to mediate the reduction of cytochrome C by xanthine oxidase and to increase the rate of NADPH oxidation.
Alias	NSC-151912, L-6868

Chemical Properties

Molecular Weight	510.5
Formula	C₂₈H₂₂N₄O₆
Cas No.	2315-97-1
Smiles	[O-][N+]([O-])=O.[O-][N+]([O-])=O.C[n+]1c2ccccc2c(-c2c3ccccc3[n+](C)c3ccccc23)c2ccccc12
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (156.71 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9589 mL	9.7943 mL	19.5886 mL	97.9432 mL
5 mM	0.3918 mL	1.9589 mL	3.9177 mL	19.5886 mL
10 mM	0.1959 mL	0.9794 mL	1.9589 mL	9.7943 mL
20 mM	0.0979 mL	0.4897 mL	0.9794 mL	4.8972 mL
50 mM	0.0392 mL	0.1959 mL	0.3918 mL	1.9589 mL
100 mM	0.0196 mL	0.0979 mL	0.1959 mL	0.9794 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NSC151912NSC 151912LucigeninL6868L 6868Inhibitorinhibit