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m-PEG11-acid is a non-cleavable 11-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) [1] and as a PEG-based linker for PROTAC synthesis [2].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | 35 € | 5 days | |
10 mg | 48 € | 5 days |
Description | m-PEG11-acid is a non-cleavable 11-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) [1] and as a PEG-based linker for PROTAC synthesis [2]. |
In vitro | ADCs consist of an antibody linked to a cytotoxin through an ADC linker[1]. PROTACs have two ligands joined by a linker: one targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs use the ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Molecular Weight | 544.63 |
Formula | C24H48O13 |
Cas No. | 2280998-74-3 |
Relative Density. | 1.113 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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