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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | m-PEG10-amine is a 10-unit polyethylene glycol (PEG) linker that is non-cleavable. It serves as an essential component in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, m-PEG10-amine functions as a PEG-based linker in the synthesis of PROTACs[1], effectively facilitating their formation. |
In vitro | ADCs consist of an antibody linked to a cytotoxin via an ADC linker[1]. PROTACs feature two ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to a target protein, utilizing the ubiquitin-proteasome system to degrade target proteins selectively[1]. |
Molecular Weight | 471.58 |
Formula | C21H45NO10 |
Cas No. | 1383658-09-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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