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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | m-PEG4-NH-DBCO is a PEG-based linker for PROTACs that connects two essential ligands, critical for forming PROTAC molecules, and facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 494.58 |
Formula | C28H34N2O6 |
Cas No. | 2228857-36-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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