m peg4 nh dbco

m-PEG4-NH-DBCO is a PEG-based linker for PROTACs that connects two essential ligands, critical for forming PROTAC molecules, and facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Boc-NH-PEG4-CH2COOH is a cleavable ADC linker utilized in the development of antibody-drug conjugates (ADC)[1].

m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Boc-NH-PEG4-CH2CH2NH2 is a cleavable 5-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

DBCO-PEG4-NHS ester is a PEG-based PROTAC linker utilized in PROTAC synthesis[1].

m-PEG-OH (MW5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker suitable for synthesizing PROTACs [1].

m-PEG-CH2COOH (MW 5000) is a polyethylene glycol (PEG) derived PROTAC linker used in the synthesis of PROTACs. [1]

m-PEG-acrylate (MW 20000), a PEG-based PROTAC linker, serves as a useful component in the synthesis of PROTACs[1].

N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

DBCO-PEG4-alcohol is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DM1-(PEG)4-DBCO is a drug-linker conjugate that combines the potent microtubulin inhibitor mertansine (DM1) with the DBCO-PEG4-Ahx linker for developing antibody-drug conjugates (ADCs). This conjugation aims to mitigate systemic toxicity associated with maytansine while improving tumor-specific delivery, leveraging DM1’s ability as an antibody-conjugatable maytansinoid.

m-PEG-OH (MW 2000) is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands to form PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

m-PEG4-CH2COOH is a PEG-based linker for PROTACs that combines two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

DBCO-C3-PEG4-NH-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5 is a polyethylene glycol (PEG) derived linker commonly used in PROTAC synthesis [1].

Ald-Ph-PEG4-NH-Boc, a PEG-based linker for PROTACs, connects two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(m-PEG4)-N'-(amino-PEG3)-Cy5 is a polyethylene glycol (PEG)-based linker compound used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Fmoc-NH-PEG4-alcohol, a PEG-based linker for PROTACs, connects two essential ligands necessary for forming PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate that combines the microtubulin inhibitor DM1 (mertansine), an antibody-conjugatable maytansinoid designed to reduce systemic toxicity and improve tumor-specific delivery, with the linker DBCO-PEG4-Ahx, for developing antibody drug conjugates (ADCs).

Carboxyrhodamine 110-PEG4-DBCO is a PEG-based PROTAC linker used in PROTAC synthesis [1].

m-PEG-NH2 (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-mal (MW 20000) is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

The compound N-(m-PEG4)-N'-(PEG3-Mal)-Cy5 is a PEG-based PROTAC linker utilized for the synthesis of PROTACs[1].

DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

m-PEG-NH2 (MW 10000) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-mal (MW 2000) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

N-(m-PEG4)-N'-(azide-PEG4)-Cy3 is a polyethylene glycol (PEG)-derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

m-PEG3-S-PEG4-propargyl is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation using the ubiquitin-proteasome system within cells.

Mal-PEG4-Lys(TFA)-NH-m-PEG24 is a polyethylene glycol (PEG) derivative designed as a PROTAC linker for synthesizing proteolysis targeting chimeras (PROTACs) [1].

m-PEG-Succinimidyl Succinate (MW 5000) is a polyethylene glycol (PEG)-based linker with succinimidyl succinate functionality, mainly used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

NH-bis(m-PEG4) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

DBCO-PEG4-NH-Boc is a PEG-based linker for PROTACs, which joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG4-sulfonic acid is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a polyethylene glycol (PEG) based linker commonly used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

m-PEG-CH2COOH (MW 20000) functions as a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

m-PEG-NH2 (MW 1000) is a PEG-based linker for PROTACs that connects two essential ligands, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker)[1].

N-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

DBCO-NH-PEG7-C2-NHS ester is a polyethylene glycol (PEG) derived linker with a terminal DBCO moiety, functioning as an N-hydroxysuccinimide (NHS) ester, and suitable for the efficient synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Mal-PEG4-Lys(t-Boc)-NH-m-PEG24 is a polyethylene glycol (PEG)-based PROTAC linker, ideal for PROTAC synthesis[1].

DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively) [1].

Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double-cleavable PEG linker (3-unit and 4-unit) designed for antibody-drug conjugation (ADC).

DBCO-C3-PEG4-amine is a PEG-based linker for PROTACs that joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a polyethylene glycol (PEG)-based linker crucial for synthesizing proteolysis targeting chimeras (PROTACs)[1].

APN-PEG4-DBCO is a cleavable linker for antibody-drug conjugates (ADCs), consisting of a four-unit PEG and a DBCO moiety, used in ADC synthesis[1].

m-PEG-thiol (MW 20000) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG-triethoxysilane (MW 5000) is a polyethylene glycol-based PROTAC linker suitable for synthesizing PROTACs[1].

m-PEG-Aminooxy (MW 2000) is a polyethylene glycol (PEG) derived PROTAC linker, primarily used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

m-PEG-azide (MW 10000), a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.