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Macropa-NCS
😃Good
Catalog No. T11936Cas No. 2146095-31-8
Macropa-NCS is a macropa bifunctional analog with antitumor activity and can be used to study prostate cancer.
Macropa-NCS
😃Good
Catalog No. T11936Cas No. 2146095-31-8
Macropa-NCS is a macropa bifunctional analog with antitumor activity and can be used to study prostate cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | 5.039 € | 3-6 months | |
| 50 mg | 6.607 € | 3-6 months | |
| 100 mg | 8.792 € | 3-6 months |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Macropa-NCS is a macropa bifunctional analog with antitumor activity and can be used to study prostate cancer. |
| In vitro | A stock solution containing 4.4 mg/mL Macropa-NCS was prepared in 0.1 M pH 9.1 NaHCO3 buffer, which also contained 0.154 M NaCl, and the solution was stored at -80 °C. Macropa-NCS (52 μL) and NaHCO3 buffer (266 μL) were added to the saline in the Tmab (74 μL) fraction, which ultimately resulted in concentrations of 5.1 mg/mL and 0.59 mg/mL for Tmab and Macropa-NCS, respectively. based on the molecular weight of Macropa-NCS of 1045.76 g/mol, the molar excess ratio of Macropa-NCS with respect to Tmab was calculated to be approximately 16-fold. [1] |
| Molecular Weight | 589.66 |
| Formula | C27H35N5O8S |
| Cas No. | 2146095-31-8 |
| Smiles | O=C(O)C=1N=C(C=CC1)CN2CCOCCOCCN(CC3=NC(=CC(N=C=S)=C3)C(=O)O)CCOCCOCC2 |
| Relative Density. | 1.33 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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