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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Mal-PEG3-PFP ester is a PEG-based linker for PROTACs, facilitating the combination of two essential ligands, thereby crucial in the formation of PROTAC molecules. This linker promotes selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase while the other binds to the target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Molecular Weight | 467.34 |
Formula | C19H18F5NO7 |
Cas No. | 1807534-78-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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