mal-peg-3-pfp ester

Mal-PEG3-PFP ester is a PEG-based linker for PROTACs, facilitating the combination of two essential ligands, thereby crucial in the formation of PROTAC molecules. This linker promotes selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG1-NHS ester is a cleavable, PEG-based linker utilized in the synthesis of antibody-drug conjugates (ADCs) and PROTACs, serving as both an ADC linker and a PROTAC linker. [Mal-PEG1-NHS ester]

NHPI-PEG2-C2-Pfp ester is a noncleavable 2-unit polyethylene glycol (PEG) linker widely used in the synthesis of antibody-drug conjugates (ADCs).

Mal-amido-PEG1-C2-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker that incorporates a maleimide functional group and an N-hydroxysuccinimide (NHS) ester. The NHS ester offers a means to specifically modify primary amines (-NH2) present in proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

m-PEG-mal (MW 5000) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Mal-PEG-Succinimidyl Valerate (MW 20000) is a polyethylene glycol (PEG)-based linker with a molecular weight of 20000, crucial for synthesizing proteolysis targeting chimeras (PROTACs).

Methyltetrazine-PEG8-PFP ester is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

Mal-amido-PEG4-TFP ester, a PEG-based PROTAC linker, finds utility in the synthesis of PROTACs[1].

Diketone-PEG11-PFP ester serves as a PEG-based PROTAC linker for PROTAC synthesis[1].

DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC). It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2].

Mal-NH-PEG12-CH2CH2COOPFP ester is a polyethylene glycol (PEG) based linker molecule designed specifically for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Mal-NH-PEG16-CH2CH2COOPFP ester is a polyethylene glycol-based linker designed for synthesizing proteolysis targeting chimeras (PROTACs) [1].

Mal-NH-PEG10-CH2CH2COOPFP ester is a polyethylene glycol (PEG)-based linker molecule used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Bis-PEG-TFP ester (MW 5000) is a polyethylene glycol (PEG) based linker compound utilized in synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

Hydroxy-PEG3-PFP ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

N3-PEG4-C2-Pfp ester is a noncleavable, four-unit polyethylene glycol linker used in the fabrication of antibody-drug conjugates (ADCs).

NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker used for synthesizing PROTACs [1].

Cyclooctyne-O-PFP ester is utilized as an ADC cytotoxin to link antibodies and linkers [1].

Mal-NH-PEG2-CH2CH2COOPFP ester, a polyethylene glycol (PEG) derived linker, is specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Ald-Ph-amido-PEG2-C2-Pfp ester is a non-cleavable 2-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies and drugs.

Mal-NH-PEG8-CH2CH2COOPFP ester is a PEG-based PROTAC linker used in the synthesis of PROTACs [1].

Mal-PFP ester is a alkyl ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Mal-PEG36-NHS ester is a PEG-based linker used in PROTAC development, joining two essential ligands to form PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

HO-PEG-mal (MW 3400) is a PEG-based linker for PROTACs, joining two essential ligands necessary for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG3-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, which are crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a polyethylene glycol (PEG)-based linker crucial for synthesizing proteolysis targeting chimeras (PROTACs)[1].

Mal-PEG-mal (MW 2000) is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Diketone-PEG4-PFP ester is a polyethylene glycol (PEG) derivative used as a PROTAC linker in the construction of proteolysis-targeting chimeras (PROTACs) [1].

Biotin-amido-PEG4-PFP ester is a Polyethylene glycol (PEG)-based PROTAC linker used in the synthesis of PROTACs [1].

Bis-PEG1-PFP ester is a non-cleavable ADC linker with a 1-unit PEG moiety, designed for synthesizing antibody-drug conjugates (ADCs) [1].

DBCO-PEG4-PFP ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-mal (MW 30000) is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG-mal (MW 5000) is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Mal-N-bis(PEG4-NHS ester) is a polyethylene glycol (PEG)-based bifunctional linker used for synthesizing Proteolysis Targeting Chimeras (PROTACs) [1].

NHS-PEG4-(m-PEG12)3-ester is a polyethylene glycol (PEG)-based linker used for PROTAC synthesis [1].

Mal-PEG1-PFP ester, an alkyl ether-based PROTAC linker, is utilized in PROTAC synthesis.

HO-PEG-mal (MW 5000) is a PEG-based linker for PROTACs that connects two essential ligands necessary for forming PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system in cells.

Bis-PEG13-PFP ester, a PEG-based linker for PROTACs, joins two essential ligands to form PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-NH-PEG24-CH2CH2COOPFP is a polyethylene glycol (PEG)-based ester, serving as a PROTAC linker in the synthesis of PROTACs[1].

Ald-Ph-amido-PEG3-C2-Pfp ester is a noncleavable antibody-drug conjugate (ADC) linker, classified as a polyethylene glycol (PEG) linker.

Mal-amido-PEG24-TFP ester is a polyethylene glycol (PEG)-derived linker utilized for PROTAC synthesis [1].

DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor used as a toxin payload in antibody-drug conjugates, is conjugated via a DBCO-(PEG)3-vc-PAB linker.

Azido-PEG8-PFP ester is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating the formation of PROTAC molecules. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG6-NHS ester is a noncleavable ADC linker comprising a Maleimide functional group, a 6-unit Polyethylene Glycol (PEG) spacer, and an N-Hydroxysuccinimide (NHS) ester moiety.

PC Mal-NHS carbonate ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. This chemical compound facilitates drug-antibody conjugation, enabling targeted delivery and enhanced therapeutic efficacy. Its unique carbonate ester structure allows efficient cleavage in the targeted environment, ensuring controlled drug payload release, highlighting its significance in innovative and targeted cancer therapies.

Mal-amido-PEG12-TFP ester is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Bis-Mal-Lysine-PEG4-TFP ester, a PEG-based PROTAC linker, facilitates PROTAC synthesis[1].

Bis-PEG9-PFP ester is a PEG-based linker for PROTACs [which joins two essential ligands, crucial for forming PROTAC molecules]. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Boc-PEG-t-butyl ester is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system within cells.